Pubblications

485. A Circular Economy Strategy for Repurposing Heparin Manufacturing By-Products as Anti-Inflammatory Therapeutics. Uslenghi E, Kandola T, Nizzolo S, Saunders E, Gee Jun T,  Skidmore MA, Yates EA, Guerrini M, Lima AM, Bisio A. Proteoglycan Res, 2025 3:e70032. https://doi.org/10.1002/pgr2.70032

486. Heparin and Heparinoids—Far More Than Just Anticoagulants. Bendas G, Bisio A. Editorial to the special Issue “Heparin and Heparinoids”,Proteoglycan Res. 2025 3:e70028. https://doi.org/10.1002/pgr2.70028.

484. Modelling the Detailed Conformational Effects of the Lactosylation of Hyaluronic Acid. Elli S, Sisto T, Nizzolo S, Freato N, Bertocchi L, Bianchini G, Yates EA, Guerrini M. Biomacromolecules, 2025, 26, 541−555, https://doi.org/10.1021/acs.biomac.4c01318.

483. Synthetic glycol-split heparin tri- and tetrasaccharides provide new insights into structural peculiarities for antiheparanase activity. Ni M, Parafioriti M, Esposito E, Danzi M, Cano O, Muzi L, Kayal Y, Ferro V, Vlodavsky I, Elli S, Naggi A, Petitou M, Guerrini M. Bioorganic & Medicinal Chemistry, 2025 118,118052.

482. Cardiovascular Symposium on Perspectives in Long COVID. Dieter RS, Kempaiah P, Dieter EG, Alcazar A, Tafur A, Gerotziafas G, Gonzalez Ochoa A, Abdesselem S, Biller J, Kipshidze N, Vandreden P, Guerrini M, Dieter RA Jr, Durvasula R, Singh M, Fareed J. Clin Appl Thromb Hemost 2025, 31:10760296251319963. doi: 10.1177/10760296251319963. PMID: 39943820; PMCID: PMC11822813.

477. Chitosan derivatives as dynamic coatings for transferrin glycoform separation in capillary electrophoresis, Porpiglia, NM, Tagliaro I, Pellegrini B, Antonini C, Bertini S. Int J Biol Macromol, 2024, 254, 127888. https://doi.org/10.1016/j.ijbiomac.2023.127888

476. A novel biomimetic probe for galectin‐3 recognition: Chemical synthesis and structural characterization of a β‐galactose branched sodium hyaluronate. Nizzolo S, Esposito E, Ni M, Bertocchi L, Bianchini G, Freato N, Zanzoni S, Guerrini M, Bertini S. Proteoglycan Res. 2024;2:e19. https://doi.org/10.1002/pgr2.19

475. Carbohydrate-based antithrombotics. Bisio A., Guerrini G., Naggi A. Chapter in Carbohydrate-Based Therapeutics, Adamo R. and Lay L. Eds., 2024 Wiley-VCH, Weinheim, 353-380. https://doi.org/10.1002/9783527831326.ch11

474. Characterization of Cyclodextrin Cross-linked Polymers Used in Environmental Applications by Solid-state NMR Spectroscopy: a Historical Review. Lacalamita D, Bertini S, Mongiovì C, Cosentino C, Crini N, Torri G, Fourmentin M, Naggi A, Formentin S, Guerrini M, Crini G. in The Environment in a Magnet Applications of NMR Techniques to Environmental Problems, 2024; DOI: 10.1039/BK9781837671250-00316.

473. Differential Solvent DEEP-STD NMR and MD Simulations Enable the Determinants of the Molecular Recognition of Heparin Oligosaccharides by Antithrombin to Be Disentangled. Parafioriti, M., Elli, S., Muñoz-García, J. C., Ramírez-Cárdenas, J., Yates, E. A., Angulo, J., Guerrini, M. (2024). Int J Mol Sci, 25(9), 4669. https://doi.org/10.3390/ijms25094669

472.Different Drug Mobilities in Hydrophobic Cavities of Host–Guest Complexes between β-Cyclodextrin and 5-Fluorouracil at Different Stoichiometries: A Molecular Dynamics Study in Water. Raffaini G, Elli S, Catauro M, D’Angelo A. Int. J. Mol. Sci. 2024, 25, 5888. https://doi.org/10.3390/ijms25115888

471. Chitosan derivatives as dynamic coatings for transferrin glycoform separation in capillary electrophoresis. Porpiglia N.M., Tagliaro I., Pellegrini B., Alessi A., Tagliaro F., Russo L., Cadamuro F., Musile G., Antonini C., Bertini S. International Journal of Biological Macromolecules, Volume 254, Part 2, January 2024, 127888

470. Molecular modeling and phylogenetic analyses highlight the role of amino acid 347 of the N1 subtype neuraminidase in influenza virus host range and interspecies adaptation. Elli S, Raffaini G, Guerrini M, Kosakovsky Pond S and Matrosovich M (2023) Front. Microbiol. 14:1309156. doi: 10.3389/fmicb.2023.1309156

469. Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1)–a promising target for the immunotherapy of cancer. Lopez V, Schuh HM, Mirza S, Vaaßen VJ, Schmidt MS, Sylvester K, Naggi A,   Scheffler B,  Lee S-Y,  Bendas G, Müller CE. Frontiers in Immunology, 2023., 14, 1173634. https://doi.org/10.3389/fimmu.2023.1173634

468. Development of a cascade production system finalized to the extraction of all-tomatine-rich fraction using the tomato cannery waste as feedstock Abbasi-Parizad P, Salvino RA, Passera A , Follador ARV , Cosentino C, Jucker C, Savoldelli S , Bacenetti J, Casati P , Scaglia B. Journal of Cleaner Production 2023, 401, 136743https://doi.org/10.1016/j.jclepro.2023.136743

467. Blended heparin: a new perspective to guarantee the supply of a life-saving drug? Guerrini M. Clinical and Applied Thrombosis/Hemostasis 2023, 29, 1-2.

466. Quantitative 2D 1H, 13C HSQC NMR spectroscopy for the determination of chondroitin sulfate and dermatan sulfate content in danaparoid sodium. Gardini C., Boccardi G., Guerrini M., Kellenbach E., Lunenburg M., van der Meer JY., Naggi A., Urso E. Thromb Haemost 2023 DOI https://doi.org/10.1055/s-0043-1768225.

465. Analysis of Heparin Samples by Attenuated Total Reflectance Fourier-Transform Infrared Spectroscopy in the Solid State. Devlin A.J., Mycroft-West C.J., Turnbull J.E., Lima M.A., Guerrini M., Yates E.A., Skidmore M.A. ACS central 2023, https://doi.org/10.1021/acscentsci.2c01176

464. A sulphated glycosaminoglycan extract from Placopecten magellanicusinhibits the Alzheimer’s disease β-Site amyloid precursor protein cleaving enzyme 1 (BACE-1). Mycroft -West C.J., Devlin A.J., Cooper L.C., Guimon S.E., Procter P., Miller, G.J., Guerrini M., Fernig D.G., Yates E.A., Lima M.A., Skidmore M.A. Carbohydr. Res. 2023, 525, 108747.

463. Evidence for multiple binding modes in the initial contact between SARS-CoV-2 spike S1 protein and cell surface glycans. Parafioriti M., Ni M., Petitou M., Mycroft-West C.J., Rudd T.R., Gandhi N. S., Ferro V., Turnbull J. E., Lima M.A., Skidmore M. A., Fernig G., Yates E.A., Bisio A., Guerrini M., Elli S. Chem Eu. J. 2023, 29, e2022025

462. Chitosan-based coatings with tunable transparency and superhydrophobicity : A solvent-free and fluorine-free approach by steroyl derivatization, Tagliaro I., Seccia S., Pellegrini B., Bertini S., Antonini C.,  Carbohydrate Polymers, 2023, https://doi.org/10.1016/j.carbpol.2022.120424.

461. 3D bioprinted colorectal cancer models based on hyaluronic acid and signalling glycans Cadamuro F., Marongiu L., Marino M., ` Tamini N., Nespoli L., Zucchini N., Terzi A., Altamura D., Gao Z., Giannini C., Bindi G., Smith A., Magni F., Bertini S., Granucci F., Nicotra F., Russo L.,  Carbohydrate Polymers, 2023, 120395.

460. Further advances in identification of pentosan polysulfate monosaccharide composition by NMR Eisele G., Alekseeva A., Bertini B., Gardini C., Paganini D., Montatixe Fonseca E. C., Guerrini M., Naggi A, , Journal of Pharmaceutical and Biomedical Analysis 235 (2023) 115672.

459. Carbohydrate-based antithrombotics. In “Carbohydrate-Based Therapeutics” Bisio A., Guerrini G., Naggi A., Adamo R. and Lay L. Eds Wiley-VCH, Weinheim, 353-380 (2023)

458. Glycosaminoglycans: What Remains to be Deciphered?  Perez S., Mashkakova O, Angulo J., Bedini E., Bisio A., de Paz J.L., Fadda E., Guerrini M., Hricovini M., Hricovini M., Lisacek F., Nieto P., Pagel K., Paiardi G., Richter R., Samsonov S., Vives R., Nikitovic D., Ricard-Blum S. JACS Au https://doi.org/10.1021/jacsau.2c00569  PMC10052243