Recent Publications 2018-2020

  1. NMR spectroscopy and chemometric models to detect a specific non-porcine ruminant contaminant in pharmaceutical heparin. Colombo E., Mauri L., Marinozzi M., Rudd T.R., Yates E.A., Ballabio D., Guerrini M. 2022 J. Pharm. Biomed. Anal. 214, 114724
  2. Initial contact between SARS-CoV-2 spike S1 protein and cell surface glycans involves multiple binding modes. Parafioriti M., Ni M., Petitou M., Mycroft-West M.J., Rudd T.R., Gandhi N.S., Ferro V., Turnbull J.E., Lima M.A., Skidmore M.A., Fernig D.G., Yates E.A., Bisio A., Guerrini M., and Elli S. ChemRχiv. 2022, DOI: 26434/chemrxiv-2022-21brb
  3. Pentosan polysulfate inhibits attachment and infection by SARS-CoV-2 in vitro: insights into structural requirements for binding. Bertini S., Alekseeva A., Elli S., Pagani I., Zanzoni S., Eisele G., Krishnan R., Maag K.P., Reiter C., Lenhart D., Gruber R., Yates E.A., Vicenzi E., Naggi A., Bisio A., Guerrini M. 2022 Thromb. Haemost. 122, 867-880.


  1. Evidence of a putative glycosaminoglycan binding site on the glycosylated SARS-CoV-2 spike protein N-terminal domain Schuurs ZP, Hammond E, Elli S, Rudd TR, Mycroft-West CJ, Lima MA, Skidmore MA, Karlsson R, Chen YH, Bagdonaite I, Yang Z, Ahmed YA, Richard DJ, Turnbull J, Ferro V, Coombe DR, Gandhi NS. Comput Struct Biotechnol J. 2021;19:2806-2818.
  1. Combined Analytical Approaches to Standardize and Characterize Biomaterials Formulations: Application to Chitosan-Gelatin Cross-Linked Hydrogels Magli, S. Rossi, L. Cosentino, C. Bertini S., Nicotra F., and Russo, L. Biomolecules 2021, 11, 683.
  1. Enisamium is an inhibitor of the SARS-CoV-2 RNA polymerase and shows improvement of recovery in COVID-19 patients in an interim analysis of a 3 clinical trial. Holubovska, H., Bojkova, D., Elli, S., Bechtel, M., Boltz, D., Muzzio, M., Peng, X., Sala, F., Cosentino, C., Mironenko, A., Milde, J., Lebed, Y., Stammer, H., Goy, A., Guerrini, M., Mueller, L., Cinatl, J., R Margitich, V., Velthuis, AJW. (2021) medRxiv


  1. Glycosaminoglycans as Tools to Decipher the Platelet Tumor Cell Interaction: A Focus on P-Selectin. Schwarz S, Gockel LM, Naggi A, Barash U, Gobec M, Bendas G, Schlesinger M. Molecules. 2020 Feb 26;25(5). doi:10.3390/molecules25051039.
  2. Pentosan polysulfate to control hepcidin expression in vitro and in vivo. Asperti M, Denardo A, Gryzik M, Castagna A, Girelli D, Naggi A, Arosio P, Poli M. Biochem Pharmacol. 2020 Feb 20;175:113867. doi: 10.1016/j.bcp.2020.113867.
  3. In-depth structural characterization of pentosan polysulfate sodium complex drug using orthogonal analytical tools. Alekseeva A, Raman R, Eisele G, Clark T, Fisher A, Lee SL, Jiang X, Torri G, Sasisekharan R, Bertini S. Carbohydr Polym. 2020 Apr 15;234:115913. doi: 10.1016/j.carbpol.2020.115913.