A new study reveals that ovine heparin is unusually rich in 3-O-sulfated glucosamine residues — concentrated at the non-reducing end of the chains in highly sulfated sequences unrelated to anticoagulant activity. This distinctive trait may serve as a structural marker of ovine heparin — and points to a valuable new opportunity: ovine-derived heparin could become […]
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Size and conformation of pentosan polysulfate (PPS) and its fractions, and their interaction with platelet factor 4 (PF4), achieved by sampling their physicochemical properties using orthogonal analytical techniques including dynamic light scattering, zeta potential, isothermal titration calorimetry, circular dichroism, atomic force microscopy, and enzyme immunoassay. Read the full article here: https://doi.org/10.1021/acsomega.5c11319
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